We must not overlook the role ...

We must not overlook the role that extremists play. They are the gadflies that keep society from being too complacent or self-satisfied; they are, if sound, the spearhead of progress. If they are fundamentally wrong, free discussion will in time put an end to them.
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 Abraham Flexner

Quotes from the same author

A patient had a 50-50 chance of benefiting from visiting a physician as of 1910. Medicine was more like voodoo than science until the 20th Century.
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 Abraham Flexner
We feel strongly that the spirit characteristic of America at its noblest, above all the pursuit of higher learning, cannot admit of any conditions as to personnel other than those designed to promote the objects for which this institution is established, and particularly with no regard whatever to accidents of race, creed, or sex.
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 Abraham Flexner
Curiosity, which may or may not eventuate in something useful, is probably the most outstanding characteristic of modern thinking ... Institutions of learning should be devoted to the cultivation of curiosity, and the less they are deflected by the consideration of immediacy of application, the more likely they are to contribute not only to human welfare, but to the equally important satisfaction of intellectual interest, which may indeed be said to have become the ruling passion of intellectual life in modern times.
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 Abraham Flexner