It is better to be a human being dissatisfied than a pig satisfied; better to be Socrates dissatisfied than a fool satisfied. And if the fool, or the pig, are of a different opinion, it is because they only know their own side of the question.
Accordingly, France Had Voltaire, and his school of negative thinkers, and England (or rather Scotland) had the profoundest negative thinker on record, David Hume: a man, the peculiarities of whose mind qualified him to detect failure of proof, and want of logical consistency, at a depth which French skeptics, with their comparatively feeble powers of analysis and abstractions stop far short of, and which German subtlety alone could thoroughly appreciate, or hope to rival.
Men and governments must act to the best of their ability. There is no such thing as absolute certainty but there is assurance sufficient for the purposes of human life.