If scientific analysis were conclusively to demonstrate certain claims in Buddhism to be false, then we must accept the findings of science and abandon those claims.
A lot of people change for good. Some people just fall off. Just trying to progress in anything, no matter what you're doing, I feel like any progression you make... some people aren't gonna be around you that were around you.
Don't settle in the land of barely enough. That is where you are, it is not who you are. That's your location, it's not your identity. No matter what it looks like, have an abundant mentality.
Material objects give rise to physical happiness, while spiritual development gives rise to mental happiness. Since we experience both physical and mental happiness, we need both material and spiritual development. This is why, for our own good and that of society we need to balance material progress with inner development.