As a confirmed melancholic, I can testify that the best and maybe only antidote for melancholia is action. However, like most melancholics, I suffer also from sloth.
The real work of men was hunting meat. The invention of agriculture was a giant step in the wrong direction, leading to serfdom, cities, and empire. From a race of hunters, artists, warriors, and tamers of horses, we degraded ourselves to what we are now: clerks, functionaries, laborers, entertainers, processors of information.