The material which a ...

The material which a scientist actually has at his disposal, his laws, his experimental results, his mathematical techniques, his epistemological prejudices, his attitude towards the absurd consequences of the theories which he accepts, is indeterminate in many ways, ambiguous, and never fully separated from the historical background . This material is always contaminated by principles which he does not know and which, if known, would be extremely hard to test.
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 Paul Feyerabend

Quotes from the same author

Human paint, produce films and videos; they dance, dream and make music; they engage in political action, exchange goods, perform rituals, build houses start wars, act in plays, try to please patrons- and so on... They contain patterns, press the practitioners to "conform" and in this way mold their thought, their perception, their actions, and their discriminative abilities.
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 Paul Feyerabend
The only absolute truth is that there are no absolute truths.
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 Paul Feyerabend
All religions are good 'in principle' - but unfortunately this abstract Good has only rarely prevented their practitioners from behaving like bastards.
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 Paul Feyerabend
The world we inhabit is abundant beyond our wildest imagination. There are trees, dreams, sunrises; there are thunderstorms, shadows, rivers; there are wars, flea bites, love affairs; there are the lives of people, Gods, entire galaxies. The simplest human action varies from one person and occasion to the next-how else would we recognize our friends only from their gait, posture, voice, and divine their changing moods? Only a tiny fraction of this abundance affects our minds. This is a blessing, not a drawback.
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 Paul Feyerabend
Yes, the academic world is screwed up, and there is nothing you can do about it. But don't worry about that. Just do what you want. If you know what you want to do and advocate for it, no one will put any energy into stopping you.
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 Paul Feyerabend