The hardest thing is to go to ...

The hardest thing is to go to sleep at night, when there are so many urgent things needing to be done. A huge gap exists between what we know is possible with today's machines and what we have so far been able to finish.
 Donald Knuth

Quotes from the same author

I remember that mathematicians were telling me in the 1960s that they would recognize computer science as a mature discipline when it had 1,000 deep algorithms. I think we've probably reached 500.
 Donald Knuth
The psychological profiling [of a programmer] is mostly the ability to shift levels of abstraction, from low level to high level. To see something in the small and to see something in the large.
 Donald Knuth
Programming is legitimate and necessary academic endeavour.
 Donald Knuth
...One of the most important lessons, perhaps, is the fact that SOFTWARE IS HARD. From now on I shall have significantly greater respect for every successful software tool that I encounter. During the past decade I was surprised to learn that the writing of programs for TeX and Metafont proved to be much more difficult than all the other things I had done (like proving theorems or writing books). The creation of good software demand a significiantly higher standard of accuracy than those other things do, and it requires a longer attention span than other intellectual tasks.
 Donald Knuth