In general, I'm careful when I'm dealing with subjects of deep cultural importance and write with abandon when I'm dealing with issues of personal dysfunction.
People with antisocial personality disorders aren't automatically bad - they simply approach the world with a more ruthless set of lenses. The lack of empathy or very weak empathy and the ability to read other people's weak spots can be a flammable combination when you get in the way of something they want. But they aren't a different species. They're a part of our spectrum.