I am not able to instruct ...

I am not able to instruct you. I can only tell that I have chosen wrong. I have passed my time in study without experience; in the attainment of sciences which can, for the most part, be but remotely useful to mankind. I have purchased knowledge at the expense of all the common comforts of life: I have missed the endearing elegance of female friendship, and the happy commerce of domestic tenderness.
I am not able to instruct you. I can only tell that I have chosen wrong. I have passed my time in study without experience; in the attainment of sciences which can, for the most part, be but remotely useful to mankind. I have purchased knowledge at the expense of all the common comforts of life: I have missed the endearing elegance of female friendship, and the happy commerce of domestic tenderness.

Quotes from the same author

If a man does not make new acquaintances as he advances through life, he will soon find himself left alone. A man, sir, should keep his friendship in a constant repair.
To keep your secret is wisdom; but to expect others to keep it is folly.
Love is the wisdom of the fool and the folly of the wise.
Memory is the mother of all wisdom.
Friendship, like love, is destroyed by long absence, though it may be increased by short intermissions.