From the dawn of exact ...

From the dawn of exact knowledge to the present day, observation, experiment, and speculation have gone hand in hand; and, whenever science has halted or strayed from the right path, it has been, either because its votaries have been content with mere unverified or unverifiable speculation (and this is the commonest case, because observation and experiment are hard work, while speculation is amusing); or it has been, because the accumulation of details of observation has for a time excluded speculation.
From the dawn of exact knowledge to the present day, observation, experiment, and speculation have gone hand in hand; and, whenever science has halted or strayed from the right path, it has been, either because its votaries have been content with mere unverified or unverifiable speculation (and this is the commonest case, because observation and experiment are hard work, while speculation is amusing); or it has been, because the accumulation of details of observation has for a time excluded speculation.
 Thomas Huxley

Quotes from the same author

If the perpetual oscillation of nations between anarchy and despotism is to be replaced by the steady march of self-restraining freedom, it will be because men will gradually bring themselves to deal with political, as they now deal with scientific questions.
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 Thomas Huxley
No delusion is greater than the notion that method and industry can make up for lack of mother-wit, either in science or in practical life.
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 Thomas Huxley
Perhaps the most valuable result of all education is the ability to make yourself do the thing you have to do, when it ought to be done, whether you like it or not. It is the first lesson that ought to be learned and however early a man's training begins, it is probably the last lesson that he learns thoroughly.
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 Thomas Huxley
There is nothing of permanent value (putting aside a few human affections) nothing that satisfies quiet reflection--except the sense of having worked according to one's capacity and light to make things clear and get rid of cant and shams of all sorts.
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 Thomas Huxley
Follow humbly wherever and to whatever abyss Nature leads, or you shall learn nothing.
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 Thomas Huxley